AstraZeneca today announced results from two international, large-scale clinical studies which further confirm that CRESTOR (rosuvastatin) lowers LDL (or bad) cholesterol, raises HDL (or good) cholesterol, enabling more patients to achieve their cholesterol goals; better than the same and even some higher doses of other currently available treatments, including atorvastatin. ...
January 01 1970 01:00:00.


Rosuvastatin calcium (Crestor)

HMG-CoA reductase is the rate limiting enzyme that converts HMG-CoA to mevalonate, a precursor of cholesterol. Cholesterol and triglycerides (TG) are synthesized in the liver. Prior to secretion into the circulation, cholesterol and TG are incorporated into lipoprotein complexes (very-low-density-lipoprotein, intermediate-density-lipoprotein, and low-density-lipoprotein). An ...
July 23 2008 16:45:10.


Hispanic PR Wire - AstraZeneca s CRESTOR(R) (rosuvastatin calcium) Receives FDA Approval

CRESTOR is the newest member of the cholesterol-lowering statin (HMG-CoA reductase inhibitors) class of drug therapy. In a six-week dose-ranging placebo-controlled study using a 5, 10, 20 or 40 mg dose, CRESTOR lowered LDL-cholesterol by 45 to 63 percent (7 percent for placebo), and increased HDL-cholesterol by 8 to 14 percent (3 percent for placebo). In a comparative clinica...
September 07 2007 10:36:14.


Crestor Drug Information

Rosuvastatin is a cholesterol-lowering medication that blocks the production of cholesterol (a type of fat) in the body. It works by reducing levels of "bad" cholesterol (low-density lipoprotein, or LDL) and triglycerides in the blood, while increasing levels of "good" cholesterol (high-density lipoprotein, or HDL).There may be other drugs not listed that can affect rosuvasta...
September 07 2007 10:36:09.


Crestor Information from Drugs.com

Crestor is a cholesterol-lowering medication that blocks the production of cholesterol (a type of fat) in the body. It works by reducing levels of "bad cholesterol (low-density lipoprotein, or LDL) and triglycerides in the blood, while increasing levels of "good cholesterol (high-density lipoprotein, or HDL).There may be other drugs not listed that can affect Crestor. Tell yo...
September 07 2007 10:36:08.


News Room

Results of the IRIS study demonstrate that CRESTOR 10 mg reduced LDL-C by 45 percent compared to 40 percent with atorvastatin 10 mg (p

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A double-blind, randomised, placebo-controlled, parallel-group, multicentre, phase III study to assess the impact of rosuvastatin treatment for 26 weeks (titrated to a maximum dose of 40mg once daily) on left ventricular function, cytokines and lipid parameters in patients with established systolic chronic heart failure.A study to evaluate the Use of Rosuvastatin in subjects ...
September 07 2007 10:36:04.